The First Baby Is Born Through In Vitro Fertilisation
A birth in northern England opened a new path to parenthood.
On 25 July 1978, Louise Brown was born at Oldham General Hospital in Oldham, England, having been conceived through work carried out at nearby Dr Kershaw's Cottage Hospital in Royton. Her delivery marked the first successful birth of a human conceived through in vitro fertilisation, a clinical procedure in which an egg is fertilised by sperm outside the human body. The Latin phrase in vitro literally translates to in glass, reflecting early biological experiments that cultivated biological tissues in glassware such as test tubes or petri dishes. Although popular media quickly adopted the informal phrase test tube babies to describe children conceived this way, laboratory procedures typically made use of wider and shallower petri dishes to culture the cells.
The clinical breakthrough in England was achieved through the collaborative work of physiologist Robert Edwards, gynaecologist Patrick Steptoe, and embryologist Jean Purdy. In Louise Brown's case, the team used natural cycle in vitro fertilisation, meaning her mother did not receive drug treatment to stimulate the ovaries. Decades after their work transformed reproductive medicine, Edwards received the Nobel Prize in Physiology or Medicine in 2010. Steptoe and Purdy could not be considered for the honour because the Nobel Prize is not awarded posthumously, and both had died before the award was granted.
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Sources
- Press release: The 2010 Nobel Prize in Physiology or Medicine (Nobel Foundation)
- Manchester celebrates forty years since first test tube baby birth (University of Manchester)
- New wall mounted plaque at The Royal Oldham Hospital honours nurses involved in historic birth of world's first IVF baby (Northern Care Alliance NHS)
- Subhas Mukherjee pioneered IVF in India, but the government refuted his work (ThePrint)
- Nobel Prize in Medicine 2010 (Indian Pediatrics)
- More than 8 million babies born from IVF since the world's first in 1978 (ESHRE)
- Total IVF births soar to more than 13 million (UNSW Sydney)
- In vitro fertilisation
Image: Dr Elena Kontogianni